According to a joint study carried out in Córdoba in which the Virology Institute of the National University School of Medicine, the Rawson Hospital, the Córdoba Ministry of Health and the Central Laboratory of the province participated, vaccines against the coronavirus neutralize the Delta, although to a lesser extent than the rest of the variants.
“This study shows that there is a decrease in what is called neutralizing antibodies against the Delta variant. This means that one must be alert and contribute to plan some reinforcement in vaccination in those who are vaccinated or in those vaccinated and who have already had the infection, “he explained Miguel Diaz, director of the Rawson hospital.
In dialogue with Radio University, the specialist said that “vaccines in general produce an immediate immune response and a delayed response and there is a whole immunological issue that develops in a vaccinated person, exposed again to the virus,” said Díaz.
On the other hand, the professional argued that the study shows the importance of applying the two doses of the Covid 19 vaccineSince a person with a single dose does not respond the same in terms of neutralizing antibodies as a person with two.
Key data from the Cordoba study:
309 plasma samples from individuals recovered from natural infection and from people vaccinated with two doses of the AstraZeneca, Sinopharm and Sputnik V vaccines, with or without a history of previous infection, were studied.
“The results indicate that the antibodies against SARS-CoV-2 pre-existing in the population in Córdoba, both the product of natural infection, and those generated by the three vaccines applied: Sputnik V, AstraZeneca y Sinopharm, after the second dose, they are able to neutralize the Delta variant, although in a reduced way “, it is inferred from the investigation.
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For this comparative analysis, 309 plasma samples from individuals corresponding to the following categories were studied:
1-41 individuals recovered from a SARS-CoV-2 virus infection of original pandemic variants.
2- 78 individuals vaccinated with two doses of AstraZeneca, of which 21 had a history of infection prior to vaccination.
3- 101 individuals vaccinated with two doses of Sinopharm, of which 40 had a history of infection prior to vaccination.
4-89 individuals vaccinated with two doses of Sputnik V, of which 55 had a history of infection prior to vaccination.
The overall neutralization average was 5.78 against the original coronavirus and dropped to 3.7 against Delta.
The results show that, considering all the individuals evaluated globally and without differentiating them by groups, A significantly lower neutralizing potency against Delta of pre-existing antibodies is observed in the vaccinated population and in individuals recovered from natural virus infection.
In the evaluation of the groups of vaccinated people, it can be observed that the highest neutralizing antibody titers against Delta are reached in the group of people vaccinated with two doses of Sputnik V and who had an infection prior to vaccination.
Secondly, the least protection would be those who have only two doses of Sinopharm, without previous infection.
Finally, it should be remembered that Delta’s community circulation has already been demonstrated in Córdoba.