Acute hepatitis in children could be related to the coronavirus

Most patients present with gastrointestinal symptoms and then progress to jaundice and, in some cases, acute liver failure. In the world there are 450 cases and at least 12 deaths. Nine cases were registered in our country.

As part of the investigation into cases of severe hepatitis of unknown origin that continue to spread throughout the world, The Lancet magazine published a scientific study in which they investigated the causes of several of the detected cases of the disease, as published TheTribune.

“Recently, there have been reports of children with a severe acute form of hepatitis in the UK, Europe, the US, Israel and Japan. Most patients present with gastrointestinal symptoms and then progress to jaundice and, in some cases, acute liver failure. So far, no common environmental exposures have been found and an infectious agent remains the most plausible cause”, indicated the researchers.

They stated that SARS-CoV-2 was identified in 18% of reported cases in the UK and in 11 (11%) of the 97 cases in England with available data who tested positive for SARS-CoV-2 on admission. ; three other cases had tested positive in the 8 weeks prior to admission.

“Ongoing serological tests are likely to show an increased number of children with severe acute hepatitis and SARS-CoV-2 infection previous or current. 11 of 12 Israeli patients were reported to have had COVID-19 in recent months, and the majority of reported hepatitis cases were in patients too young to be eligible for COVID-19 vaccines.



The authors clarified that acute hepatitis has been reported in children with multisystem inflammatory syndrome, but coinfection with other viruses was not investigated. And they came to the following conclusion: “We hypothesized that recently reported cases of severe acute hepatitis in children could be a consequence of adenovirus infection with intestinal trophism. in children previously infected with SARS-CoV-2 and carriers of viral reservoirs.

In Argentina there are nine cases that are being closely followed by national health authorities. In Santa Fe, a boy was transplanted in a hospital in the city of Rosario and was recovering from the operation. Meanwhile, in San Juan, a 2-year-old boy remains hospitalized at the Guillermo Rawson Hospital, as confirmed by the Epidemiology Division of the Ministry of Health of that province, and is being investigated and treated as a possible case of hepatitis of unknown origin.

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